An axially chiral phenanthroline ligand bearing two BINOL units was found to be capable of promoting the copper-catalyzed enantioselective arylation of 2-azonaphthalenes with arylboronic acids. This atroposelective Michael-type addition affords a range of enantioenriched axially chiral biaryl compounds in synthetically useful yields with enantiomeric ratios of up to 91.5:8.5.
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Cen et al. (2024) studied this question.
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