Temporal dynamic change patterns of intrinsic brain activity in multidomain brain networks in subcortical stroke patients

This study aimed to explore the temporal dynamic change patterns and the mechanisms of verbal memory deficit in chronic subcortical stroke patients with motor pathway based on the static and dynamic amplitude of low-frequency fluctuations. A total of 136 patients and 88 normal controls were included in the study. We found verbal memory deficits in the patients of chronic subcortical stroke involving the motor pathway, especially in patients with partial recovery. Moreover, subcortical stroke-induced functional deficits may not only occur in the motor system but also in the cognitive functional system.