Improving Image Quality While Reducing Geometric Distortion of Diffusion-weighted MRI in prostate: Comparison of FOCUS-MUSE, MUSE, and SS DWI

The current study investigated the qualitative and quantitative image quality of three DWI sequences of the prostate: SS DWI, MUSE DWI and a new DWI sequence named FOCUS-MUSE DWI. Twenty-three healthy volunteers were enrolled. The diagnostic image quality score was assessed by two radiologists on the three DWI sequences. And the ADC values in the peripheral and transitional zone were measured together with the Dice Coefficient calculated for quantitative comparison. Our results indicated that FOCUS-MUSE DWI had a superior image quality and more stable ADC measurement compared with SS DWI and MUSE DWI. The geometric distortion level was also reduced.