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A new pulse sequence was developed to selectively probe the signals of γ-aminobutyric acid (GABA). Different with the previous pulse sequences, the signal selectivity of this pulse sequence is achieved by preparation and reconversion of the 1H spin singlet order (SSO) of GABA. The optimal control method was used in the design of the pulse sequence. By using the developed pulse sequence, the 1H signals of GABA in human brains were selectively probed.
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Yang et al. (2024) studied this question.
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