Combined Multiparameter Quantitative MRI of PD, T1, T2 and the Diffusion Tensor with MP6-qMRI-Turbo Spin Echo with SPLICE

Purpose: To augment the qMRI multi-parametricity of the Triple TSE to additionally include primary diffusion tensor imaging (DTI) functionality and with seamless geometric compatibility with the nPD, T1, and T2 maps of the Triple-TSE framework. Methods: qMRI maps were generated with algorithms based on Bloch and Bloch-Torrey equations. Results: histogram analyses for the phantom and volunteer reveal well behaved qMRI data for nPD, T1, T2, MD, and FA. Conclusion: Creating a unified clinical MP-qMRI protocol for PD, T1, T2 and diffusion tensor seems within reach.