Assessing Ventilation Dynamics of Lung Transplantation with Free-Breathing Hyperpolarized Xenon-129

This is the authors' abstract. We don't add key points for this paper.

Regional quantification of ventilation dynamics can provide valuable insights into the functional changes associated with both unilateral and bilateral lung transplantation, potentially improving diagnostic monitoring and providing a better understanding of underlying pathophysiology. By imaging hyperpolarized xenon-129 (HXe) continuously over an extended period of time, ventilation dynamics more representative of steady-state, physiological breathing were derived and used to assess differences between unilateral and bilateral transplant patients.