Texture analysis of area-at-risk based on T1-mapping associated with infarct characteristics following acute STEMI

To assess the potential of texture analysis (TA) of area-at-risk (AAR) based on native T1 mapping in predicting the severity of injury in ST-segment elevation myocardial infarction (STEMI) patients. Cine, T1 mapping, and late gadolinium enhancement (LGE) images were analyzed to evaluate cardiac function, and scar characteristics. The predictive value of TA for adverse LV remodeling (ALVR) and large final infarct size was evaluated. Entropy and uniformity (parameters of TA) in AAR of T1 mapping were highly correlated with convalescent infarct size, uniformity independently predicted large final infarct size, however, TA of AAR was not associated with convalescent ALVR.