Associations between cross-sectional area and white matter area within the rostral spinal cord and gray matter volume in left supplementary motor area and right middle cingulate gyrus suggest a concordant change pattern and adaptive mechanisms for neuronal plasticity underlying remote neurodegeneration in early cervical spondylotic myelopathy. The atrophy of cross-sectional area within the upper spinal cord and gray matter volume loss in right postcentral gyrus can serve as potential neuroimaging biomarkers of early structural changes within spinal cord and brain preceding marked clinical disabilities in patients with cervical spondylotic myelopathy.
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Kuang et al. (2024) studied this question.
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