Preoperative prediction of Ki-67 expression of hepatocellular carcinoma using T1 mapping on gadoxetic acid-enhanced MRI

The cell proliferation index, Ki-67 labeling index (LI) indicates the status of cell proliferation activity which corresponds with tumor biological behavior, treatment efficacy and prognosis. If the preoperative Ki-67 expression status in HCC can be accurately predicted noninvasively, it may provide important information for clinical decision-making. T1 mapping is useful for preoperative prediction of Ki-67 LI of HCC. The nomogram Combining T1 mapping on gadoxetic acid-enhanced MRI and clinical indicators has good predictive efficacy for preoperative prediction of Ki-67 LI, which can promote the individualized risk stratification and further treatment decision of HCC patients.