Intravoxel incoherent motion and diffusion kurtosis imaging can be used to assess the differentiation degree of non-small cell lung cancer

The purpose of this study was to assess differentiation degree of non-small cell lung cancer (NSCLC) by using intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI). There were statistically significant differences in D and Dapp values between the poorly differentiated group and the moderately and highly differentiated group (p＞0.05). D value had the best diagnostic efficacy in evaluating the differentiation degree of NSCLC [area under the curve (AUC) =0.773]. Our study demonstrated that D value derived from IVIM and Dapp derived from DKI can distinguish the differentiation degree of NSCLC.