Comparison of test–retest reliability of structural, resting state functional, and diffusion tensor magnetic resonance imaging

We measured imaging reproducibility in structural, resting state fMRI and diffusion tensor scans across different time points and scanners in healthy volunteers. First, we assessed structural imaging variability by calculating volume for seven subcortical structures. Second, we evaluated across-scanner and across-time reliability of rsfMRI by assessing temporal signal-to-noise ratio of five networks. Finally, we assessed variability in diffusion metrics across scanners and time points. Our results provide statistical validations for longitudinal work on multiple systems, especially for structural study. The influence of different equipment in rsfMRI and DTI related research may be considered, especially DMN and GCC analysis involved.