Because of its anatomical situation, the brainstem is difficult to image. With whole brain acquisitions, we end up with artifactual images. Our team developed a brainstem-dedicated T2*-weighted MRI acquisition method. Using this, we imaged the brain of sixteen healthy volunteers. This sequence was repeated 5 times for each volunteer. Our MRI protocol also consisted of a three-dimensional T1-weighted whole-brain sequence. The aim was to reduce the number of acquisitions required to visualize the nigrosome-1 by using image processing methods. We quantified the quality of the images by using image quality assessment indices and had one criterion: the visualization of nigrosome-1.
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Houidef et al. (2024) studied this question.
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