In this work we develop a confidence map algorithm to identify reliable estimates of PDFF and R2* for CSE-MRI in the liver. Reliability of estimates is evaluated based on a normalized root-mean-square-error (NRMSE) between measured and model signals. Threshold values of the NRMSE are determined by using the Cramér–Rao Lower Bound. Monte-Carlo simulations and clinical CSE-MRI successfully validate the proposed method.
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Tamada et al. (2024) studied this question.
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