Multiparametric MRI radiomic model for diagnosing focal cortical dysplasia and laterality

Focal cortical dysplasia (FCD) is the most common epileptogenic developmental malformation which remains challenging to diagnose. This study aimed to investigate the possibility of diagnosing FCD and laterality in epilepsy patients using the multiparametric MRI radiomics model. Radiomic features were extracted from the preoperative MRI images of 86 patients. Multivariable logistic regression was used to develop the diagnosis model. The performance of radiomic model was evaluated with general evaluation metrics and was compared with that of inexperienced radiologists. We concluded that radiomics features derived from the combined of T1WI, T2WI and FLAIR might help diagnosing FCD and laterality.