Comparison and combination of CT and MRI radiomics for early prediction of pathological response to neoadjuvant chemotherapy in gastric cancer

This is the authors' abstract. We don't add key points for this paper.

To compare and combine CT and multi-parametric MRI (mp-MRI) radiomics for early prediction of pathologic response to neoadjuvant chemotherapy (NAC) in locally advanced gastric cancer (LAGC). The CT radiomics model, mp-MRI radiomics model and the combined nomogram were all associated with pathologic response. The multi-modal nomogram containing both CT and MRI radiomics scores exhibited added predictive ability and was linked to patients’ outcome. The CT and MRI radiomics model exhibited equivalent capability. This study proposed a multi-modal radiomics nomogram by incroperating concurrent CT and MRI images, which presents favorable efficacy in predicting treatment response to NAC in LAGC.