We developed a high-volume, low error UV-curable hydrogel formation process that can target specific T1 and T2 parameters. Our process relies on the polymerization of water-soluble photoinitiator TPO-Lithium in acrylamide (monomer), polyethylene-glycol-diacrylate (crosslinker), de-ionized (DI) water, and paramagnetic ions. We characterize the linearizing effect of varying paramagnetic ion concentrations in determining T1 and T2 values, and present an application to construct a quantitative anatomy-mimicking brain slice phantom containing UV gels.
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Tung et al. (2024) studied this question.
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