Significant Signal-to-Noise Ratio (SNR) Enhancement with Ultrahigh Dielectric Constant (uHDC) Ceramic Disks for 2H MRSI Application at 7T

This is the authors' abstract. We don't add key points for this paper.

Ultrahigh-field (UHF) deuterium (2H) magnetic resonance spectroscopy imaging (DMRSI) is valuable to study neuroenergetics by quantitatively measuring the energy metabolic rates in the human brain. However, the low intrinsic signal-to-noise ratio (SNR) of deuterium signal due to its low gyromagnetic ratio and low metabolites concentration has been a technical challenge to achieving high imaging resolution. In this study, we have integrated ultrahigh dielectric constant (uHDC) ceramic disks with an 8-channel 2H-1H human head array coil to largely improve the receive sensitivity and DMRSI SNR (>60%) at 7T, aiming for human brain metabolic imaging application.