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Existing commercial body MR-guided focused ultrasound (MRgFUS) systems have limited electronic steering ranges and rely on mechanical translation/rotation to ablate large tissue volumes. Here, we describe a flat fully-populated MRgFUS phased array body system with increased electronic steering capabilities. Following extensive benchtop and pre-clinical testing, the device was evaluated in a pilot clinical trial of MRgFUS for the treatment of uterine fibroids, which demonstrated the feasibilty and safety of the approach. The technology is extensible, stackable, and modular, allowing custom MRgFUS device development tailored to any indication.
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Jones et al. (2024) studied this question.
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