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MRI is one of the best imaging techniques in clinical analysis because it is non-invasive and has high resolution. Contrast agents are used to further improve these images, as they increase the level of soft tissue detail, differentiating regions of interest. Currently, Gd-based contrast agents have important precautions. In this work we present a new nanoparticle based on iron oxide, with 4 nm and positive contrast (T1-weighted). Thus, effects similar to gadoteric acid, with reduced signal persistence and partial renal excretion, indicating great stability, this new paramagnetic nanoparticle has great potential to be applied as a contrast agent in MRI.
Chaim et al. (Wed,) studied this question.