This study investigated the values of standardized volume and intravoxel incoherent motion (IVIM) parameters of spleen in evaluating tumor burden and prognosis in newly diagnosed acute leukemia (AL). Eighty-five AL patients and seventy-four healthy volunteers were recruited and underwent IVIM in the abdomen on a 3.0T MRI system. The results showed standardized volume and IVIM parameters of spleen were associated with tumor burden and treatment response in AL, and 218.1cm3 was the threshold of standardized spleen volume for predicting treatment response, which indicated that they can be potentially useful in tailoring the individualized treatment plan for each patient.
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Bian et al. (2024) studied this question.
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