We recruited 4 patients with internal carotid artery occlusive diseases and assessed whether 4D-MR angiography can be used as a noninvasive alternative to intraarterial DSA. All patients were imaged with TOF-MRA, 4D-PACK, 4D-S-PACK, and DSA. 4D-PACK demonstrated a sensitivity, specificity, and accuracy of 100%, 100%, and 100% respectively, as same as TOF-MRA, for diagnosing ICAO in reference to DSA. Moreover, 4D-PACK along with 4D-S-PACK could provide additional dynamic information on compensatory circulation after ICAO. Our results showed that non-contrast 4D-MR angiography has the potential to become an alternative imaging approach in diagnosing ICAO and initially assessing its blood supply pattern.
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Zhang et al. (2024) studied this question.
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