Improved Dynamic In Vivo pH Imaging Using Hyperpolarized 13C-bicarbonate

This is the authors' abstract. We don't add key points for this paper.

We present a dynamic pH measurement using metabolite-specific gradient-echo spiral sequence with flow suppression to improve the SNR of bicarbonate and CO2 with short T2* and used bipolar gradients to suppress the high bicarbonate signal in the vessel. With the improved image quality and high temporal resolution, it is possible to measure the dynamic pH in vivo. Future studies will work to increase the sample size to confirm these results.