Improved Visualization of the Medial Medullary Lamina with Phase Prior Reconstruction in Quantitative Susceptibility Mapping

Morphology Enabled Dipole Inversion (MEDI) is an iterative reconstruction algorithm for Quantitative Susceptibility Mapping (QSM) that is effective in suppressing artifacts by exploiting the magnitude image as a morphological prior. Use of a phase prior such as the local field to determine the $L₁$ regularization term results in improved visualization of the medial medullary lamina as measured by the contrast-to-noise ratio and was preferred by a radiologist over the magnitude prior in each case.