Assessment of association between body composition contents and liver fibrosis in the patients with sarcopenic obesity

Sarcopenic obesity is a disease which associates both sarcopenia and obesity and may trigger worse clinical outcomes including hepatic manifestation of fat accumulation and musculoskeletal disabilities. It is likely that sarcopenia and obesity share common physiological pathways and are interconnected through the muscle-liver-adipose tissue axis. Assessment of muscle mass is a key for the whole-body insulin-mediated glucose metabolism and energy homeostasis. However, it is little known the interconnection between hepatic fibrosis and sarcopenic obesity. This study compared body composition contents in non-obese and sarcopenic obese patients using abdominal MRIs and investigated the relationship between hepatic fibrosis and sarcopenic obesity factors.