Super-resolution reconstruction of time-resolved four-dimensional computed tomography (TR-4DCT) with multiple breaths based on TR-4DMRI

This study has demonstrated that the feasibility to reconstruct multiple-breath TR-4DCT via the super-resolution reconstruction framework through either CT4D→(MRBH→MRFB) or (CT4D←MRBH)→ MRFB deformable image registration. Using TR-4DCT, potential dosimetry consequences in radiotherapy of lung, liver, and pancreatic patients due to patient breathing irregularities can be readily assessed.