Association of brain connections in anterior and posterior circulation with the side of asymptomatic internal carotid stenosis and verbal memory

Previous studies have reported that patients with asymptomatic internal carotid stenosis (aICS) had recall verbal memory impairment. However, the underlying mechanism to elucidate the altered functional connectivity (FC) associated with the anterior and posterior circulation was not proposed. Furthermore, whether the laterality of aICS is a factor in FC alterations and verbal memory impairment requires further investigation. In this study, we reported that the left and right aICS groups showed different patterns of FC changes related to secondary language regions in anterior and posterior circulation. These FCs could be served as imaging biomarkers for recall verbal memory.