Test-Retest Repeatability of Smart BrainQuant (STAGE) of the healthy brain at 1.5T

Smart BrainQuant, adapted from strategically acquired gradient echo (STAGE) method, is capable to provide 10 multi-contrast and multi-quantitative images with high image quality in 4:21 minutes at 1.5T. A preclinical validation work was introduced in this study with the aim to assess the test-retest repeatability of T1, proton spin density (PSD), susceptibility, and R2* by recruiting 18 healthy volunteers. Coefficient of variation of T1, PSD, and R2* ranged from 3.3% to 4.1%. Bland-Altman demonstrated that the line of equality is in the 95% confidence interval (CI) of the mean difference for the four maps.