Patients with medulloblastoma treated with radio-chemotherapy (N=211) were examined by perivascular space (PVS) imaging at three time points: 0, 3, and 12 months. The patients were treated with different dose level based on risk factors. For low dose radiation, there were no significant changes in PVS between time points. A transient increase in PVS was observed for high and standard dose radiation during radiotherapy which subsequently resolved during chemotherapy. Perivascular space imaging is a potential biomarker to monitor the side effects from combined modality therapy.
No takes yet. Share an insight, caveat, or question.
Song et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: