Accelerated in-vivo 23Na Multi-Quantum Coherences MRI by utilizing Low-Rank Matrix Completion

Sodium (23Na) MRI has received increased attention as a potential biomarker for disease states thanks to the advent of ultra-high field MRI. One interesting asset from 23Na MRI is the distinction between single and triple quantum signal to further characterize tissues. However, 3D 23Na multi-quantum coherences (MQC) imaging requires multiple radiofrequency phase-cycling, which is inherently time-consuming and therefore difficult to include in protocols. In this work, we propose to accelerate 23Na MQC MRI by leveraging multi-dimensional under-sampling coupled with a dedicated Low-Rank matrix completion image reconstruction.