Experimental study demonstrates that IL-6/STAT3 induces PAR-4 in hepatocellular carcinoma cells, suggesting an oncogenic role.
Prostate apoptosis response protein-4 (PAR-4) is considered a tumor suppressor. However, the role of PAR-4 in hepatocellular carcinoma (HCC) has rarely been reported. The study explores the role of PAR-4 in the malignant behaviors of HCC cells.
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Xu et al. (2024) studied this question.
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