Intracranial epidural abscess secondary to medication‐related osteonecrosis of the jaw: A case report

Background An intracranial abscess secondary to medication‐related osteonecrosis of the jaw (MRONJ) is a rare condition that can spread to the skull through continuous structures. Case presentation A 71‐year‐old man with an intracranial epidural abscess caused by MRONJ in the maxilla. Because it is refractory to conservative treatment, inflammation had spread from sphenoid sinusitis, resulting in an intracranial abscess, and then antibiotic therapy and surgical drainage contributed to successful outcomes. Conclusion Intracranial abscess should be suspected when MRONJ extends to the adjacent structure, causing sudden headache and loss of consciousness. Early surgical intervention should be considered to reduce the risk of necrosis progressing.