Liver Transplantation in Crigler-Najjar Syndrome

ÖzCrigler-Najjar syndrome is a rare, inherited disease that causes unconjugated hyperbilirubinemia.Liver transplantation is a definitive treatment option for Crigler-Najjar syndrome.Two patients with Crigler-Najjar syndrome who received liver transplantation are presented in this case report.The first patient who was misdiagnosed with Gilbert's syndrome was a 15-year-old male.He had speech and gait disturbances that partially recovered after liver transplantation.The second patient was a 22-year-old male.He developed liver fibrosis although he had a mild clinical form of the disease.Liver transplantation was successfully performed for both of these patients without significant morbidity.