Laboratory analysis reveals destabilization of low-grafted poly(ethylene glycol) liposomes by anti-PEG antibodies, suggesting limits to reduced polymer coverage.
Binding of anti-PEG antibodies to poly(ethylene glycol) (PEG) on the surface of PEGylated liposomal doxorubicin (PLD)
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Chen et al. (2024) studied this question.
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