Investigation reveals age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families, highlighting early markers in at-risk relatives.
IBD is characterised by dysbiosis, but it remains unclear to what extent dysbiosis develops in unaffected at-risk individuals. To address this, we investigated age-related patterns of faecal and serum markers of dysbiosis in high-risk multiplex IBD families (two or more affected first-degree relatives).
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Jacobs et al. (2024) studied this question.
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