A virally-encoded tRNA neutralizes the PARIS antiviral defence system

Nathaniel Burman; Svetlana Belukhina; Florence Depardieu; Royce A. Wilkinson; Mikhail Skutel; Andrew Santiago‐Frangos; Ava B. Graham; Alexei Livenskyi; Anna Chechenina; Natalia Morozova; Trevor Zahl; William S. Henriques; Murat Buyukyoruk; Christophe Rouillon; Baptiste Saudemont; Lena Shyrokova; Tatsuaki Kurata; Vasili Hauryliuk; Konstantin Severinov; Justine Groseille; Agnès Thierry; Romain Koszul; Florian Tesson; Aude Bernheim; David Bikard; Blake Wiedenheft; Artem Isaev

doi:10.1038/s41586-024-07874-3

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Abstract

Viruses compete with each other for limited cellular resources, and some deliver defence mechanisms that protect the host from competing genetic parasites

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Burman et al. (2024) studied this question.

synapsesocial.com/papers/68e5d23bb6db643587567e8d https://doi.org/10.1038/s41586-024-07874-3

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A virally-encoded tRNA neutralizes the PARIS antiviral defence system

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Abstract

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A virally-encoded tRNA neutralizes the PARIS antiviral defence system

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