We used isotope tracers, an oral glucose tolerance test, and arterialized blood sampling to determine postprandial lactate flux rates in healthy young and older men and women. Lactate rates of appearance and oxidation and the lactate‐pyruvate exchange were delayed and diminished in both enteric and systemic postprandial lactate shuttle phases in older participants.
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Arevalo et al. (2024) studied this question.
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