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August 6, 2024Cancer Immunology ImmunotherapyOpen Access

Deciphering the interplay of HPV infection, MHC-II expression, and CXCL13+ CD4+ T cell activation in oropharyngeal cancer: implications for immunotherapy

Shida Yan Xing Zhang Qiaohong Lin Mingyuan Du Yiqi Li Shuai He Jingtao Chen Xiyuan Li Jin‐Xin Bei Shuwei Chen Ming Song

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Abstract

Human papillomavirus (HPV) infection has become an important etiological driver of oropharyngeal squamous cell carcinoma (OPSCC), leading to unique tumor characteristics. However, the interplay between HPV-associated tumor cells and tumor microenvironment (TME) remains an enigma.

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Cite This Study

Yan et al. (2024) studied this question.

synapsesocial.com/papers/68e5d358b6db643587569e62 https://doi.org/10.1007/s00262-024-03789-0

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