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August 1, 2024JCO Global OncologyOpen Access

Performance of Low-Dose Immunotherapy and Standard-Dose Immunotherapy in Microsatellite Instability-High Metastatic Colorectal Cancer: Real-World Data (CLouD—High Study)

Mehak Trikha Laboni Sarkar Aditya Dhanawat Noorzia Syed Himanshu Gujarathi Manan Vora Abhishekram Raja Prabhat Bhargava Anant Ramaswamy Sarika Mandavkar Avanish Saklani Rajiv Kumar Munita Bal Omshree Shetty Subhash Yadav Vikas Ostwal

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Abstract

Standard-dose immune checkpoint inhibitors (SD-ICIs) are the standard of care as initial therapy in microsatellite instable-high (MSI-H) advanced/metastatic colorectal adenocarcinomas (mCRC), but there are preclinical data to suggest that low-dose ICIs (LD-ICI) might also have similar efficacy.

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Cite This Study

Trikha et al. (2024) studied this question.

synapsesocial.com/papers/68e5dd88b6db64358757299e https://doi.org/10.1200/go.24.00141

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