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August 1, 2024Osteoarthritis and CartilageOpen Access

Zoledronate alleviates subchondral bone collapse and articular cartilage degeneration in a rat model of rotator cuff tear arthropathy

Hiroki Tawaratsumida Tomohiro Iuchi Yusuke Masuda Takayuki Ide Shingo Maesako Takasuke Miyazaki Toshiro Ijuin Shingo Maeda Noboru Taniguchi

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Abstract

To evaluate the humeral head bone volume of patients with cuff tear arthropathy (CTA) and examine the therapeutic effect of zoledronate in a rat modified model of CTA (mCTA).

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Cite This Study

Tawaratsumida et al. (2024) studied this question.

synapsesocial.com/papers/68e5dfd6b6db643587574355 https://doi.org/10.1016/j.joca.2024.08.005

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The Use of Intravenous Zoledronate May Reduce Retear Rate after Rotator Cuff Repair in Older Female Patients with Osteoporosis: A First In-Human Prospective Studycohort · 2022 · 20 citations
2Anti-RANKL antibody treatment mitigates subchondral bone loss and cartilage degeneration without affecting synovial inflammation in a mouse model of rotator cuff tear arthropathyOriginal Research · 2026
3Intraoperative Zoledronic Acid for Arthroscopic Rotator Cuff Repair Results in Distinct Circulating Micro-RNA Profiles Indicating Improved Tendon-to-Bone HealingRCT · 2026
4Effect of zoledronate on avascular necrosis of the femoral head according to disease stage and bone resorption activityOriginal Research · 2026
5Peri‐operative zoledronic acid attenuates peri‐prosthetic osteolysis in a rat model of cemented knee replacement2024 · 1 citations

More related papers

Stepwise loss of shoulder stabilizers induces humeral head migration and progression of cuff tear arthropathy in a rat model2026
Local application of zoledronate inhibits early bone resorption and promotes bone formation2024
The calcitonin receptor controls osteophyte formation, but not cartilage degeneration and subchondral bone loss in experimental osteoarthritis2026

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