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August 1, 2024Open Access

Supplemental Figure S1 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma

Victor J. Collins Katelyn R. Ludwig Ariana E. Nelson Soumya Sundara Rajan Choh Yeung Ksenia Vulikh Kristine A. Isanogle Arnulfo Mendoza Simone Difilippantonio Baktiar Karim Natasha J. Caplen Christine M. Heske

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Abstract

A screen of multiple drug combinations demonstrates the selectivity of the synergistic activity of the DNA-PK clinical inhibitor M3814

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Collins et al. (2024) studied this question.

synapsesocial.com/papers/68e5e0e0b6db643587574b10 https://doi.org/10.1158/1535-7163.26423737.v1

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplemental Figure S1 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
2Supplemental Figure S3 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
3Supplemental Figure S3 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
4Supplemental Figure S2 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
5Supplemental Figure S2 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
6Supplemental Figure S5 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
7Supplemental Figure S4 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024
8Supplemental Figure S4 from Enhancing Standard of Care Chemotherapy Efficacy Using DNA-Dependent Protein Kinase (DNA-PK) Inhibition in Preclinical Models of Ewing Sarcoma2024