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August 1, 2024Open Access

Table S3 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors

B. Leticia Rodriguez Jiawei Huang Laura Gibson Jared J. Fradette Hung-I Harry Chen Kikuye Koyano Czrina Cortez Betty Li Carmence Ho Amir M. Ashique Vicky Y. Lin Suzanne Crawley Julie M. Roda Peirong Chen Bin Fan Jeong Kim James Sissons Jonathan Sitrin Daniel D. Kaplan Don L. Gibbons Lee B. Rivera

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Key Points

LAIR1 expression profiles across circulating immune cells and matched tumor tissue provide baseline characteristics for collagen-rich solid tumors.
Analysis of patient samples details circulating immune cells alongside matched solid tumors to characterize LAIR1 antagonist target distribution.
Evaluation of LAIR1 expression across matched tissues supports therapeutic exploration of LAIR1 antagonist combined with anti-PD1 agents.

Implication

Observational summary reports LAIR1 expression on immune cells across blood and matched tumor samples, highlighting targets for antagonist therapies.

Abstract

Summary of patient samples used for evaluating LAIR1 expression on immune cells in blood and matched tumors.

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Cite This Study

Rodriguez et al. (2024) studied this question.

synapsesocial.com/papers/68e5e0e0b6db643587574b39 https://doi.org/10.1158/1535-7163.26423803.v1

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S3 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
2Table S2 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
3Table S2 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
4Figure S1 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
5Table S1 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024

Table S1 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
Table S5 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024
Table S5 from Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors2024