Viral Hepatitis and Vitamin D Deficiency

This review aims to determine whether vitamin D levels were correlated with viral Hepatitis.Chronic liver disorders brought on by hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are frequently linked to vitamin D deficiency.According to studies, low vitamin D levels probably don't stop HBV replication and are a factor in chronic HBV infection's poor clinical results.Higher levels of vitamin D or vitamin D supplementation have been linked in meta-analyses to better sustained virological response (SVR) to interferon-based therapy in individuals with long-term HCV infection.For individuals with vitamin D levels more than 30 ng/mL, the odds ratio for reaching SVR was 1.57 (95% CI: 1.12-2.2) in comparison to those with lower levels.Furthermore, compared to healthy controls, individuals with chronic hepatitis B (CHB) had considerably decreased vitamin D levels, according to a systematic review and meta-analysis.Serum vitamin D levels and HBV viral loads were found to be inversely correlated.Patients with chronic viral hepatitis B and C are frequently found to be vitamin D deficient, and increasing vitamin D levels or supplementation may enhance treatment outcomes, especially for HCV infection.In summary, vitamin D deficiency was found to be strongly correlated with poor clinical outcomes in individuals with HBV and HCV, such as the development of liver cirrhosis and hepatocellular carcinoma.