True and false positive HIV point of care test results in a prospective multinational study of at-risk African women: implications for large-scale repeat HIV testing in HIV prevention programs

Susan Morrison; Joanne Batting; Valentine Wanga; Ivana Beesham; Jennifer Deese; G Justus Hofmeyr; Margaret P. Kasaro; Cheryl Louw; Charles Morrison; Nelly Mugo; Thesla Palanee‐Phillips; Melanie Pleaner; Krishnaveni Reddy; Caitlin W. Scoville; Jenni Smit; Jeffrey S. A. Stringer; Khatija Ahmed; Elizabeth A. Bukusi; Philip Kotze; Jared M. Baeten

doi:10.1097/qai.0000000000003497

Key Points

Point of care testing generates expected false positive and false negative outcomes during routine evaluation, affecting diagnostic accuracy.
Prospective multinational study evaluations assess testing performance across cohorts of at-risk African women participating in prevention trials.
Careful interpretation of test outcomes supports effective repeat hiv testing strategies, minimizing misclassification in hiv prevention programs.

Implication

Prospective multinational study reveals false positive results in at-risk African women, highlighting the need for accurate repeat point of care screening across prevention programs.

Abstract

Accurate HIV point of care testing is the cornerstone of prevention and treatment efforts globally, though false (both negative and positive) results are expected to occur.

Discussion

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Cite This Study

Morrison et al. (2024) studied this question.

synapsesocial.com/papers/68e5e0ecb6db6435875757c1 https://doi.org/10.1097/qai.0000000000003497

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True and false positive HIV point of care test results in a prospective multinational study of at-risk African women: implications for large-scale repeat HIV testing in HIV prevention programs

Key Points

Implication

Abstract

Discussion

Cite This Study

True and false positive HIV point of care test results in a prospective multinational study of at-risk African women: implications for large-scale repeat HIV testing in HIV prevention programs

Key Points

Implication

Abstract

Discussion

Cite This Study

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