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August 1, 2024Journal of College of Physicians And Surgeons PakistanOpen Access

Comparison of First-Line Chemotherapeutics and Validation of the EORTC Prognostic Index in Malignant Pleural Mesothelioma: Retrospective Single-Centre Experience

Yasin Sezgin Oğur Karhan Serdar İleri Senar Ebinç Sezai Tunç Zuhat Urakçı

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Abstract

Objective: To evaluate the efficiency of pemetrexed cisplatin in comparison with gemcitabine cisplatin and to validate the EORTC (European Organisation for Research and Treatment of Cancer) prognostic score in combination chemotherapy treatment for malignant pleural mesothelioma.

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Cite This Study

Sezgin et al. (2024) studied this question.

synapsesocial.com/papers/68e5e1d3b6db643587576441 https://doi.org/10.29271/jcpsp.2024.08.904

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Comparison of the Efficacy of First-Line Pemetrexed-Platinum and Gemcitabine-Platinum Regimens in Malignant Peritoneal Mesothelioma2025
2A multicentre randomised phase III trial comparing pembrolizumab versus single-agent chemotherapy for advanced pre-treated malignant pleural mesothelioma: the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trialHuman Clinical Trial · 2020 · 271 citations
3Maintenance pemetrexed after platinum pemetrexed chemotherapy and survival outcomes in malignant pleural mesothelioma in a multicenter real world studyCohort Study · 2026
4Analysis of Treatment Strategies and Outcomes in Malignant Peritoneal Mesothelioma: Insights From a Multi-Center Study2024 · 11 citations
5Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung CancerLate-Phase Clinical Trial · 2008 · 3,207 citations

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Real-world overall survival with platinum–pemetrexed chemotherapy versus ipilimumab–nivolumab in peritoneal mesothelioma: A propensity-matched multicenter analysis.2026
C31-12 Efficacy and Safety of Pembrolizumab in Treating Pleural Mesothelioma: A Network Meta-Analysis of Randomized Controlled Trials2026
Efficacy and safety of immune checkpoint inhibitors after platinum-based therapy for refractory or recurrent malignant pleural mesothelioma: A systematic review and meta-analysis.2026

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