The frequency and function of nucleoprotein-specific CD8 ⁺ T cells are critical for heterosubtypic immunity against influenza virus infection

Samuel Amoah; Weiping Cao; Ekramy E. Sayedahmed; Yuanyuan Wang; Amrita Kumar; Margarita Mishina; Devon J. Eddins; Wen-Chien Wang; Mark Burroughs; Mili Sheth; Justin Lee; Wun‐Ju Shieh; Sean D. Ray; Caitlin Bohannon; Priya Ranjan; Suresh D. Sharma; Jessica Hoehner; Robert A. Arthur; Shivaprakash Gangappa; Nobuko Wakamatsu; H. Richard Johnston; Jan Pohl; Suresh K. Mittal; Suryaprakash Sambhara

doi:10.1128/jvi.00711-24

Abstract

Cytotoxic T lymphocytes (CTLs) mediate host defense against viral and intracellular bacterial infections and tumors. However, the magnitude of CTL response and their function needed to confer heterosubtypic immunity against influenza virus infection are unknown. We addressed the role of CD8

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Amoah et al. (2024) studied this question.

synapsesocial.com/papers/68e5e3e6b6db6435875782c9 https://doi.org/10.1128/jvi.00711-24

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The frequency and function of nucleoprotein-specific CD8 ⁺ T cells are critical for heterosubtypic immunity against influenza virus infection

Abstract

Discussion

Cite This Study

The frequency and function of nucleoprotein-specific CD8 ⁺ T cells are critical for heterosubtypic immunity against influenza virus infection

Abstract

Discussion

Cite This Study

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