Introduction: heart disease is the leading cause of death in the world for both men and women.The presentation of ischemic heart disease varies depending on multiple factors, including gender.Materials and method: this was an observational, cross-sectional study with an analytical component of all patients admitted for ACS at Hospital Docente Clínico-Quirúrgico Comandante Manuel Fajardo between January 2016 and December 2020.Results: female patients had a median age of 73 (IQR: 62-80), significantly higher than males, with a higher prevalence of arterial hypertension and diabetes mellitus (n = 353 and n = 143, respectively, and p < 0.01).Age, creatinine level, and ST-elevation acute coronary syndrome (STE-ACS) were identified as triggering factors for cardiac complications (RR: 1.01; 95% CI: 1.00-1.07;p = 0.03; RR: 1.01; 95% CI: 1. 00-1.02; p = 0.01; and RR: 2.77; 95% CI: 1.31-5.87;p = 0.02, respectively).Conclusions: women with ACS were older than men, with a higher prevalence of arterial hypertension and diabetes mellitus, while the predictive variables of in-hospital cardiovascular complications were age, serum creatinine, and STE-ACS.
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