6204 Symptom load changes in patients before and after medications for postural orthostatic tachycardia syndrome

Objectives To compare the symptom burden of patients before and after commencement of medications following diagnosis of POTS (Postural orthostatic tachycardia syndrome) Methods Patients completed the Malmo POTS score questionnaire at diagnosis and 12 months following medications. Additional information was collected from the clinical records. The responses were then analysed Inclusion criteria Children who have been diagnosed with POTS following active stand test or Head up tilt test as per criteria and commenced on medications Exclusion Criteria Where the diagnosis of POTS is not confirmed or if they haven't been commenced on medications or if they haven't completed both sets of questionnaire Results 34 patients completed both sets of Malmo POTS questionnaires (scores between 0–10). There were 26 girls and 8 boys in the study with the age range being between 13- 17 years at the start of the study. These were the results obtained: Conclusion There is a high burden of dizziness, pre-syncopal symptoms, brain fog and fatigue in children with POTS. There was significant improvement in the score for dizziness, pre- syncopal symptoms and palpitations following medications. There was not much improvement in other symptom burden. This study helps to outline the likely treatment benefits against expectations during discussions before commencement of medications.