Oral Lichenoid Reaction (OLR) is a chronic inflammatory lesion of the oral mucosa that occurs as an allergic response to certain dental materials, medications and systemic diseases. The frequency of OLR in the general population has been documented to be very less. The clinical and histological features of OLR closely resemble those of Oral Lichen Planus (OLP), making it challenging to distinguish between the two clinically. OLRs might have a higher malignant potential than OLP. The diagnosis and treatment of OLR is very crucial as misdiagnosis may result in detrimental effects on the biophysical health of the patient. Here, we present case series of two patients who presented with amalgam restorations and burning sensation on the buccal mucosa while consumption of hot and spicy food. An immunohistopathological evaluation confirmed the diagnosis as Oral Lichenoid Reaction. Elimination of causative factors remain the mainstay of treatment which markedly reduces the sufferings of the patient with a commendable result.
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Roychowdhury et al. (2024) studied this question.
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