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July 26, 2024Xenobiotica

Improved preclinical drug metabolism and pharmacokinetics of pibothiadine (HEC121210), a novel hepatitis B virus capsid assembly modulator

Ming Li Xingguo Yan Li Zhang Xinchang Liu Yayi Liu Qian Wang Jing Li

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Abstract

Pibothiadine (PBD; HEC121120) is a novel hepatitis B virus capsid assembly modulator based on GLS4 (morphothiadine) and has inhibitory activities against resistant strains.

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Li et al. (2024) studied this question.

synapsesocial.com/papers/68e5ef80b6db643587584047 https://doi.org/10.1080/00498254.2024.2381223

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