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July 24, 2024Redox BiologyOpen Access

Mitochondria to plasma membrane redox signaling is essential for fatty acid β-oxidation-driven insulin secretion

Martin Jabůrek Eduardo Klöppel Pavla Průchová Oleksandra Mozheitová Jan Tauber Hana Engstová Petr Ježek

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Abstract

We asked whether acute redox signaling from mitochondria exists concomitantly to fatty acid- (FA-) stimulated insulin secretion (FASIS) at low glucose by pancreatic β-cells. We show that FA β-oxidation produces superoxide/H

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Jabůrek et al. (2024) studied this question.

synapsesocial.com/papers/68e5f2dcb6db6435875877a2 https://doi.org/10.1016/j.redox.2024.103283

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